Association of STAT4 rs7574865 with Sysceptibility to Juvenile Onset Systemic Lupus Erythematous in Pakistani Population
نویسندگان
چکیده
منابع مشابه
Association of HLA-DRB1 Alleles in Juvenile-onset Systemic Lupus Erythematosus (SLE) in Iranian Children
Introduction Systemic Lupus Erythematosus (SLE) is a complex autoimmune and inflammatory disease. Many studies show HLA alleles can be associated with SLE. The aim of this study was to determine the association of HLA-DRB1 alleles with juvenile- onset in Iranian children. Materials and Methods At a case – control study, 31 children with systemic lupus erythematosus (case group) who referred to ...
متن کاملJuvenile systemic lupus erythematous in Iranian children
Results A total of 59 patients, 49 (89%) were female and10 (16.9%) male. The female to male ratio was 4.9:1. The mean age of onset was 10.5 years (range 2-16). The mean duration of disease from diagnosis was 2 years (range7 months-5 years). The most common of constitutional sign was fatigue (76.3%) and the other signs were fever (32.2%), Nocturnal pain (20.3%), Mood disorder (20.03%), and Weigh...
متن کاملAssociation of STAT4 with susceptibility to rheumatoid arthritis and systemic lupus erythematosus in the Japanese population.
OBJECTIVE STAT4 encodes a transcriptional factor that transmits signals induced by several key cytokines, and it might be a key molecule in the development of autoimmune diseases. Recently, a STAT4 haplotype was reported to be associated with rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) in Caucasian populations. This was replicated in a Korean RA population. Interestingly, t...
متن کاملassociation of hla-drb1 alleles in juvenile-onset systemic lupus erythematosus (sle) in iranian children
introduction systemic lupus erythematosus (sle) is a complex autoimmune and inflammatory disease. many studies show hla alleles can be associated with sle. the aim of this study was to determine the association of hla-drb1 alleles with juvenile- onset in iranian children. materials and methods at a case – control study, 31 children with systemic lupus erythematosus (case group) who referred to ...
متن کاملSTAT4 rs7574865 polymorphism and the susceptibility of systemic sclerosis (SSc)
Previous study suggested that signal transducers and activators of transcription-4 (STAT4) rs7574865 polymorphism may play an important role in susceptibility to Systemic Sclerosis (SSc) in Chinese. However, no further study was conducted to confirm this result. Thus, we did a case-control study. 174 SSc patients and 202 controls were enrolled in this study. When the STAT4 rs7574865 polymorphis...
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ژورنال
عنوان ژورنال: Sains Malaysiana
سال: 2020
ISSN: 0126-6039
DOI: 10.17576/jsm-2020-4911-14